Company Filing History:
Years Active: 2001
Title: The Innovative Contributions of Guobing Xiang in Nucleic Acid Sequencing
Introduction
Guobing Xiang, based in San Diego, California, is a prominent inventor recognized for his groundbreaking work in mass spectrometry and nucleic acid sequencing. With a patent to his name, Xiang's contributions have significantly advanced the field of molecular biology.
Latest Patents
Xiang's patent, titled "Mass Spectrometric Methods for Sequencing Nucleic Acids," provides a novel approach to sequencing using RNA polymerases. This technique incorporates both DNA-dependent and RNA-dependent RNA polymerases, enhancing the traditional Sanger sequencing strategy. By generating a set of nested RNA transcripts through base-specific chain termination, these transcripts are then analyzed using mass spectrometry. Additionally, Xiang's method includes the identification of transcriptional terminator sequences or attenuator sequences, marking a significant advancement in the efficiency and accuracy of nucleic acid sequencing.
Career Highlights
Throughout his career, Guobing Xiang has made substantial contributions to the scientific community, particularly through his role at Sequenom, Inc. His innovative patent reflects a commitment to enhancing genetic research methodologies and improving the tools available to researchers in genetics and biochemistry.
Collaborations
Xiang's work is complemented by collaboration with other talented researchers, including colleagues Changwon Kang and Young-Soo Kwon. Their combined efforts contribute to an environment of innovation and progress in the biotechnology sector, fostering advancements that benefit a wide array of applications from clinical diagnostics to genetic research.
Conclusion
Guobing Xiang’s ingenuity in developing mass spectrometric methods for sequencing nucleic acids demonstrates the profound impact of innovation in molecular biology. His contributions, along with the support of his colleagues, continue to drive the frontiers of scientific discovery and technological advancement in understanding genetic materials.
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