Gunnar Malmquist

Title: Innovations of Gunnar Malmquist

Introduction

Gunnar Malmquist is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of bioprocess purification, holding a total of five patents. His work focuses on optimizing processes that enhance the efficiency and effectiveness of biotechnological applications.

Latest Patents

One of his latest patents is a method in bioprocess purification systems. This invention relates to optimizing a bioprocess purification system that includes a bioreactor designed to provide a harvest with a target composition. The purification process is arranged downstream of the bioreactor and is configured to purify the harvest to produce a target product with desired characteristics. The method involves detecting at least one quality attribute indicative of the target product's characteristics in a downstream process. It also includes identifying correlations between the quality attribute measured in the downstream process and parameters to control the cell culture process in the bioreactor. Finally, the method allows for controlling the cell culture process to meet the desired characteristics based on the identified correlations, ensuring that the target characteristics remain within a predetermined range.

Another significant patent by Malmquist is a method for baseline correction in a chromatogram. This invention discloses a method for correcting a baseline in a chromatogram obtained using a buffer with at least one UV-absorbing component, which is a weak acid or a weak base. The method includes providing a chromatography system with a chromatography column and a UV detector downstream of the column. It also involves obtaining a chromatogram with the UV detector at a specific wavelength and calculating UV absorption values of the acid and base forms from the concentrations and UV extinction coefficients.

Career Highlights

Gunnar Malmquist has worked with prominent companies in the biotechnology sector, including GE Healthcare Bio-Sciences AB and Cytiva Sweden AB. His experience in these organizations has contributed to his expertise in bioprocessing and purification technologies.

Collaborations

Throughout his career, Malmquist has collaborated with notable colleagues such as Nils Stafstrom and Hans Berg. These collaborations have likely enriched his work and contributed to the advancements in his field.

Conclusion

Gunnar Malmquist is a distinguished inventor whose work in bioprocess purification has led to innovative patents that enhance the efficiency of biotechnological processes. His contributions continue to impact the field positively.