The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Jul. 01, 2019
Cytiva Sweden Ab, Uppsala, SE;
Key Hyckenberg, Uppsala, SE;
Helena Skoglar, Uppsala, SE;
Gunnar Malmquist, Uppsala, SE;
Mikael Carlsten, Uppsala, SE;
Roger Lundqvist, Uppsala, SE;
Dan Andersson, Uppsala, SE;
Linda Mathiasson, Uppsala, SE;
Lars Mattsson, Uppsala, SE;
Sara Sendabo, Uppsala, SE;
Mikael Berg, Uppsala, SE;
Cytiva Sweden AB, Uppsala, SE;
Abstract
The present invention relates to a method for optimizing a bioprocess purification system comprising a bioreactor configured to provide a harvest comprising a target composition, and a purification process arranged downstream the bioreactor and being configured for purification of the harvest to produce a target product having a desired characteristics. The method comprising: a) detecting () at least one quality attribute indicative of characteristics of the target product in a downstream process, b) identifying () correlations between the at least one quality attribute measured in the downstream process and parameters to control a cell culture process in the bioreactor, and c) controlling () the cell culture process to meet the desired characteristics based on the identified correlations, whereby the target characteristics is within a p re-determined range.