Company Filing History:
Years Active: 2002
Title: **Guadalupe Guzman Tirado: Innovator in Dengue Virus Research**
Introduction
Guadalupe Guzman Tirado, a dedicated researcher based in Habana, CU, has made significant contributions to the field of virology through his innovative work on synthetic peptides related to the Dengue virus. His research not only enhances our understanding of this viral infection but also plays a vital role in the development of potential vaccines and therapeutic approaches.
Latest Patents
Guzman Tirado holds one patent titled **“Pre-M/M epitopes of dengue virus, synthetic peptides, chimeric proteins and their use.”** This invention encompasses five synthetic peptides derived from the pre-M/M protein of the Dengue-2 virus. The patented peptides correspond to specific amino acid sequences (3-31, 45-67, 57-92, 69-93, and 103-124) and have been thoroughly evaluated for their potential to generate an anti-peptide immune response in mice. Notably, these peptides have demonstrated the ability to elicit neutralizing antibodies against all four serotypes of the Dengue virus, indicating their significance in vaccine development.
Career Highlights
Throughout his career, Guzman Tirado has been involved in pioneering research that sheds light on complex immune responses to viral pathogens. His work has established crucial connections between synthetic peptides and immune activation, demonstrating the robustness of the immune response in both mice and humans. The success of his innovations emphasizes the importance of continuous research in combating infectious diseases.
Collaborations
Guzman Tirado has collaborated with esteemed colleagues such as Susana Vazquez Ramudo and Gerardo Enrique Guillen Nieto. Together, they have worked on advancing the understanding of the immune mechanisms involved in dengue infections, making notable strides in the field of virology. Their collaborative efforts are essential for the development of innovative strategies to mitigate the impact of Dengue virus on global health.
Conclusion
As an inventor and researcher, Guadalupe Guzman Tirado continues to push the boundaries of knowledge surrounding the Dengue virus. His patent on pre-M/M epitopes not only represents an important advancement in scientific research, but it also holds promise for future applications in vaccine development. The contributions of innovators like Guzman Tirado are vital for addressing public health challenges posed by infectious diseases.