Location History:
- Ipswich, MA (US) (2016)
- Cambridge, MA (US) (2014 - 2020)
Company Filing History:
5 out of 336 
1 out of 37 
1 out of 1 Years Active: 2014-2025
Title: Innovations of Gregory Lohman in DNA Assembly
Introduction
Gregory Lohman is a prominent inventor based in Cambridge, MA, known for his significant contributions to the field of molecular biology and DNA assembly. With a total of 7 patents, Lohman's work focuses on improving the efficiency and accuracy of DNA fragment assembly, which is crucial for various applications in genetic engineering and synthetic biology.
Latest Patents
Lohman's latest patents include innovative methods and compositions for the ordered assembly of multiple DNA fragments. One notable patent describes a synthetic self-complementary oligonucleotide that features a double-stranded region with a binding sequence for PaqCI. This oligonucleotide is designed with unligatable 3' and 5' ends that cannot be cleaved by PaqCI, allowing for precise assembly in reaction mixtures that may also include ligases and repair enzymes. Another patent focuses on improved methods for assembling large numbers of DNA fragments into a single large DNA molecule, utilizing a computer system that integrates ligation data to optimize synthetic overhangs. This method has demonstrated success in assembling complex structures, such as a viral genome and a bacterial operon, showcasing the potential of Lohman's innovations in advancing genetic research.
Career Highlights
Throughout his career, Gregory Lohman has worked with notable companies in the biotechnology sector, including New England Biolabs, Inc. and Visterra, Inc. His experience in these organizations has allowed him to develop and refine his innovative approaches to DNA assembly, contributing to advancements in the field.
Collaborations
Lohman has collaborated with esteemed colleagues, including Vladimir Potapov and John M Pryor, further enhancing the impact of his work through shared expertise and insights.
Conclusion
Gregory Lohman's contributions to DNA assembly through his innovative patents and collaborations have significantly advanced the field of molecular biology. His work continues to influence research and applications in genetic engineering, making him a key figure in the scientific community.