The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2014
Filed:
Apr. 27, 2011
A. Stewart Campbell, Framingham, MA (US);
Gregory Lohman, Cambridge, MA (US);
Obadiah J. Plante, Danvers, MA (US);
A. Stewart Campbell, Framingham, MA (US);
Gregory Lohman, Cambridge, MA (US);
Obadiah J. Plante, Danvers, MA (US);
Ancora Pharmaceuticals, Inc., Woburn, MA (US);
Abstract
The present invention provides syntheticlipooligosaccharide (LOS)-based oligosaccharides and conjugates containing variousserotype-specific oligosaccharide antigens or various coreoligosaccharide structures or motifs corresponding to one or more of the three major serotypes and/or members within a given serotype. The oligosaccharides may be synthesized by a chemical assembly methodology relying on a limited number of monosaccharide and disaccharide building blocks. The invention further providesLOS-based immunogenic and immuno-protective compositions and antibodies derived therefrom for diagnosing, treating, and preventing infections caused by