Company Filing History:
Years Active: 2009-2012
Title: Gregory Keith Miranda: Innovator in Oligonucleotide Synthesis
Introduction
Gregory Keith Miranda is a notable inventor based in Princeton, MA (US). He has made significant contributions to the field of biotechnology, particularly in the synthesis of oligonucleotides. With a total of two patents to his name, Miranda's work has implications for various applications in molecular biology and genetic research.
Latest Patents
Miranda's latest patents focus on activators for oligonucleotide synthesis. The process he developed utilizes phosphoramidite chemistry, employing a specific activator known as 1,1-dioxo-1,2-dihydro-1λ-benzo[d]isothiazol-3-one. This activator is preferably used in the presence of an organic base, enhancing the efficiency of oligonucleotide synthesis. The structural formula of the activator includes various substituents, allowing for flexibility in its application. Preferred organic bases for this process include pyridine, 3-methylpyridine, and N-methylimidazole.
Career Highlights
Gregory Keith Miranda is currently associated with Avecia Biotechnology, Inc., where he continues to innovate in the field of biotechnology. His work has been instrumental in advancing techniques that are crucial for genetic research and therapeutic development.
Collaborations
Miranda has collaborated with notable colleagues, including Nanda Dulal Sinha and William Edward Zedalis. These collaborations have contributed to the advancement of research in oligonucleotide synthesis and related fields.
Conclusion
Gregory Keith Miranda's contributions to oligonucleotide synthesis through his innovative patents highlight his role as a key figure in biotechnology. His work continues to influence the field and pave the way for future advancements.