Company Filing History:
Years Active: 2009-2013
Title: Innovations of Gregorino Paone
Introduction
Gregorino Paone is an accomplished inventor based in Rome, Italy. He has made significant contributions to the field of antimicrobial agents, particularly through his innovative work on modified defensins. With a total of 3 patents, Paone's research focuses on enhancing immune responses and treating diseases associated with inflammation.
Latest Patents
One of Gregorino Paone's latest patents is titled "Modified Defensins and Their Use." This disclosure provides modified antimicrobial agents, specifically modified defensin polypeptides. The compositions include a modified arginine residue, such as an ADP-ribosylated and/or ribosylated alpha defensin polypeptide. The patent outlines methods for modulating an immune response using these modified defensin polypeptides. Additionally, it describes techniques for modulating antimicrobial activity and inhibiting cytotoxic activity. The methods disclosed are aimed at treating diseases associated with immune responses, including inflammatory and pulmonary diseases.
Career Highlights
Gregorino Paone is affiliated with the United States of America, as represented by the Secretary, Department of Health and Human Services. His work has been pivotal in advancing the understanding and application of modified defensins in medical treatments.
Collaborations
Paone has collaborated with notable colleagues, including Joel Moss and Rodney L. Levine. Their combined expertise has contributed to the success of his research and patent applications.
Conclusion
Gregorino Paone's innovative work in the field of antimicrobial agents showcases his dedication to improving health outcomes through scientific research. His contributions continue to influence the development of new treatments for diseases related to immune responses.