Madison, WI, United States of America

Grazia Chiellini

USPTO Granted Patents = 11 


 

Average Co-Inventor Count = 4.9

ph-index = 4

Forward Citations = 54(Granted Patents)


Company Filing History:


Years Active: 2007-2015

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11 patents (USPTO):Explore Patents

Title: Grazia Chiellini: Innovator in Vitamin D Analog Research

Introduction

Grazia Chiellini is a prominent inventor based in Madison, WI (US), known for his significant contributions to the field of vitamin D analogs. With a total of 11 patents to his name, Chiellini has made remarkable strides in developing compounds that exhibit potential anti-cancer properties and therapeutic uses for various skin conditions.

Latest Patents

Chiellini's latest patents include innovative compounds such as N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses. This invention reveals that the compound demonstrates high binding activity and is effective in halting the proliferation of undifferentiated cells, promoting their differentiation into monocytes. This evidence suggests its potential as an anti-cancer agent, particularly for treating or preventing leukemia, colon cancer, breast cancer, skin cancer, and prostate cancer. Another notable patent is for 2-methylene-(20S,25R)-19,26-dinor-vitamin D analogs, which also shows pronounced activity in inhibiting undifferentiated cell proliferation. This compound is beneficial for treating skin diseases like psoriasis and conditions such as wrinkles and dry skin, while also having minimal calcemic activity, making it suitable for autoimmune disorders and inflammatory diseases.

Career Highlights

Chiellini is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research and development efforts. His work has garnered attention for its potential impact on cancer treatment and skin health.

Collaborations

Chiellini has collaborated with notable colleagues, including Hector Floyd Deluca and Lori A Plum, who have contributed to his research endeavors.

Conclusion

Grazia Chiellini's innovative work in vitamin D analogs showcases his commitment to advancing medical science and improving health outcomes. His patents reflect a dedication to addressing critical health issues, particularly in cancer treatment and skin conditions.

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