The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2015
Filed:
May. 16, 2012
Hector F. Deluca, Deerfield, WI (US);
Margaret Clagett-dame, Deerfield, WI (US);
Lori A. Plum, Arena, WI (US);
Grazia Chiellini, Madison, WI (US);
Hector F. DeLuca, Deerfield, WI (US);
Margaret Clagett-Dame, Deerfield, WI (US);
Lori A. Plum, Arena, WI (US);
Grazia Chiellini, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
This invention discloses N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs, and specifically N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-1α-hydroxyvitamin Dand pharmaceutical uses therefor. This compound exhibits relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent especially for the treatment or prevention of leukemia, colon cancer, breast cancer, skin cancer or prostate cancer.