This inventor holds 1 USPTO granted patent. Top assignee: Microbiological Research Authority. Active years: 1998.
Company Filing History:
Years Active: 1998
Title: Graham Mark Brearley: Innovator in Enzyme Production
Introduction
Graham Mark Brearley is a notable inventor based in Oaks, California. He has made significant contributions to the field of enzyme production, particularly through his innovative methods. His work has implications for various applications in biotechnology and pharmaceuticals.
Latest Patents
Graham Mark Brearley holds a patent for a method of producing phenylalanine dehydrogenase in culture. This method achieves yields of over 50 units of enzyme per liter of culture, with one unit defined as the amount required to convert one micro-mole of phenylalanine to phenyl pyruvic acid at 25°C and pH 10.8. The growth medium used in this process includes a nitrogen source, a buffer, and phenylalanine or phenylpyruvic acid at a concentration of 20 mM, along with an optional vitamin solution. Notably, using phenylalanine at about 100 mM can yield over 350 units of phenylalanine dehydrogenase enzyme per liter of culture.
Career Highlights
Graham is associated with the Microbiological Research Authority, where he applies his expertise in enzyme production. His innovative approach has positioned him as a key figure in the research community focused on biotechnological advancements.
Collaborations
Graham has collaborated with notable colleagues, including Christopher Philip Price and Peter Michael Hammond. Their combined efforts contribute to the ongoing research and development in the field of microbiology and enzyme production.
Conclusion
Graham Mark Brearley is a distinguished inventor whose work in enzyme production has the potential to impact various industries. His innovative methods and collaborations highlight the importance of research in advancing biotechnological applications.