Grace S Pereira

Title: Grace S Pereira: Innovator in Cholinergic Dysfunction Research

Introduction

Grace S Pereira is a notable inventor based in Belo Horizonte, Brazil. She has made significant contributions to the field of neuroscience, particularly in understanding cholinergic dysfunction and its implications for cognitive enhancement and treatment of related disorders.

Latest Patents

Grace S Pereira holds a patent titled "Mouse model of cholinergic dysfunction to evaluate cognitive enhancers and drugs that improve myasthenia." This patent describes recombinant non-human mammals with reduced or no expression of vesicular acetylcholine transporter protein (VAChT). These mammals exhibit impaired performance in object and social recognition, neuromuscular performance, and alterations in autonomic nervous system function compared to their wild-type counterparts. The patent also outlines methods for screening compounds for cholinergic activity and their potential in treating cholinergic neurotransmission disorders. Additionally, it provides details on nerve cells isolated from these mammals, which can be used in vitro for screening candidate compounds.

Career Highlights

Throughout her career, Grace has worked with prestigious institutions such as Duke University and Universidade Federal De Minas Gerais. Her research has focused on developing innovative models to better understand cholinergic dysfunction and its treatment.

Collaborations

Grace has collaborated with esteemed colleagues, including Marc G Caron and Vania F Prado, contributing to the advancement of research in her field.

Conclusion

Grace S Pereira is a pioneering inventor whose work in cholinergic dysfunction has the potential to impact the treatment of cognitive disorders significantly. Her innovative research and patents reflect her dedication to advancing neuroscience.