Glenn D Roberts

Title: Glenn D. Roberts: Innovator in Molecular Detection

Introduction

Glenn D. Roberts is a notable inventor based in Rochester, MN (US), recognized for his contributions to the field of molecular diagnostics. With a total of 2 patents, he has made significant advancements in the detection of Mycobacterium tuberculosis, a critical area in public health.

Latest Patents

One of his latest patents focuses on the IS6110 based molecular detection of Mycobacterium tuberculosis. This innovative method allows for rapid diagnosis of tuberculosis by detecting the IS6110 insertion element in clinical specimens. The patent describes a reliable diagnostic test that utilizes a 'Universal' specimen preparation protocol, which eliminates live organisms and purifies nucleic acids from various clinical samples. The process involves two nucleic acid primers designed to amplify IS6110 DNA with high specificity through polymerase chain reaction. The amplified DNA is then identified using a restriction endonuclease and electrophoresis based assay. This method not only minimizes time, labor, and cost but also maximizes user safety and test reliability. The complete DNA extraction, amplification, and analysis can be accomplished within an 8-hour period, achieving a sensitivity of 92% and a specificity approaching 100%. Furthermore, testing serially obtained samples from the same patient can increase the overall detection rate to 100%. Another significant patent involves detecting a genetic locus encoding resistance to rifampin in Mycobacterium tuberculosis. This method isolates DNA from biological samples and amplifies it under hybridizing conditions, allowing for the identification of M. tuberculosis or its mutants.

Career Highlights

Throughout his career, Glenn D. Roberts has worked with prominent companies in the field of diagnostics, including Chiron Diagnostic Corporation and Roche Molecular Systems, Inc. His work has significantly impacted the development of reliable diagnostic tests for tuberculosis.

Collaborations

Glenn has collaborated with notable professionals in his field, including Gurpreet S. Sandhu and Bruce C. Kline. Their combined expertise has contributed to the advancement of molecular detection techniques.

Conclusion

Glenn D. Roberts stands out as an innovator in the field of molecular diagnostics, particularly in the detection of Mycobacterium tuberculosis. His patents reflect a commitment to improving diagnostic methods, ultimately enhancing public health outcomes.