The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 01, 1997
Filed:
May. 26, 1994
David H Persing, Rochester, MN (US);
John J Hunt, Rochester, MN (US);
Karen K Young, San Ramon, CA (US);
Teresa A Felmlee, Oronoco, MN (US);
Glenn D Roberts, Rochester, MN (US);
A Christian Whelan, Rochester, MN (US);
Roche Molecular Systems, Inc., Branchburg, NJ (US);
Mayo Foundation For Medical Education and Research, Rochester, MN (US);
Abstract
A method is provided for detecting M. tuberculosis or mutants thereof, particularly rifampin-resistant MTB, in a biological sample comprising: isolating DNA from the biological sample; amplifying the isolated DNA under hybridizing conditions with a primer set that targets portions of the gene encoding rpoB; wherein the pimer set comprises at least one primer that hybridizes under hybridizing conditions to at least one signature nucleotide for M. tuberculosis; and isolating and sequencing the amplified DNA to determine the presence or absence of M. tuberculosis or mutants thereof.