Glen D Leesman

Title: Glen D Leesman: Innovating Drug Design and Compound Libraries

Introduction

Glen D Leesman is an accomplished inventor based in Hamilton, MT, USA, known for his significant contributions to the field of pharmacokinetics and drug design. With a notable total of seven patents to his name, Leesman has pioneered innovative methods that enhance the screening and production of compound libraries, paving the way for improved drug development processes.

Latest Patents

Among Glen D Leesman's latest patents is the "Method for Screening and Producing Compound Libraries," which details a sophisticated approach to creating secondary compound libraries. This method utilizes a screening process that evaluates test samples through in vivo absorption profiles created from initial dose data and in vitro bioavailability parameters, including permeability and solubility. The aim is to identify compounds from a primary compound library that exhibit desired absorption profiles.

Another significant patent is the "Pharmacokinetic-Based Drug Design Tool and Method." This patent introduces a comprehensive PK tool designed to predict the absorption characteristics of administered compounds. The tool integrates a physiologic-based simulation model tailored to the selected route of administration, incorporating differential equation solvers to optimize the prediction of in vivo absorption. This innovation not only facilitates drug design but also assists in the selection and preparation of drug compounds for mammalian disorders.

Career Highlights

Glen D Leesman has built a distinguished career in the biomedical field, making his mark with innovative inventions that address critical challenges in drug development. His work has been influential in enhancing the efficacy of pharmaceutical compounds, which ultimately aids in the creation of more effective treatments for various health conditions.

Collaborations

Throughout his career, Leesman has collaborated with esteemed professionals such as Patrick J Sinko and Gordon L Amidon, bringing together expertise that complements his own in the field of pharmacokinetics. He has also been associated with reputable organizations, including Lion Bioscience AG and the University of Michigan, which have provided platforms for his pioneering research and inventions.

Conclusion

Glen D Leesman stands out as a key figure in the realm of innovations related to drug design and compound library production. His patents and collaborative efforts demonstrate a commitment to advancing the field of pharmacokinetics. As he continues to influence medical science, Leesman's work remains foundational in shaping the future of pharmaceutical development.