Company Filing History:
Years Active: 2022
Title: Giuseppina Maria Incisivo: Innovator in GLP-1 Analogues
Introduction
Giuseppina Maria Incisivo is a notable inventor based in Villadose, Italy. She has made significant contributions to the field of biochemistry, particularly in the synthesis of GLP-1 analogues. Her innovative work has led to advancements in the manufacturing processes of these important peptides.
Latest Patents
Giuseppina holds a patent for a "Process for the manufacture of GLP-1 analogues." This invention provides a method for producing GLP-1 analogues with high yield and purity through fragment condensation on a solid phase. The process involves a convergent synthesis that includes the condensation of a C-terminal pseudoproline fragment A with a fragment B bound to a solid support. Following this, deprotection and cleavage from the support occur, leading to the final purification of the desired peptide. Additionally, her invention outlines intermediates that are useful in the manufacturing process.
Career Highlights
Giuseppina is currently employed at Fresenius Kabi Ipsum S.r.l., where she continues to apply her expertise in peptide synthesis. Her work has been instrumental in enhancing the efficiency and effectiveness of pharmaceutical manufacturing processes.
Collaborations
Throughout her career, Giuseppina has collaborated with esteemed colleagues, including Andrea Orlandin and Antonio Ricci. These partnerships have fostered a collaborative environment that promotes innovation and the sharing of knowledge in the field.
Conclusion
Giuseppina Maria Incisivo's contributions to the synthesis of GLP-1 analogues exemplify her dedication to advancing biochemistry. Her innovative processes and collaborations highlight her role as a leading inventor in her field.