Company Filing History:
Years Active: 1999-2009
Title: Giuseppina Di Stefano: Innovator in Antiviral Drug Conjugation
Introduction
Giuseppina Di Stefano is a prominent inventor based in Bologna, Italy. She has made significant contributions to the field of pharmaceutical sciences, particularly in the development of innovative drug conjugates. With a total of 2 patents, her work focuses on enhancing the efficacy of antiviral drugs through novel conjugation techniques.
Latest Patents
One of her latest patents is titled "Process for the preparation of doxorubicin conjugates with lactosaminated human albumin." This invention describes a procedure for conjugating hydrazone derivatives of doxorubicin to lactosaminated human albumin (L-HSA). The method utilizes trialkylphosphines to reduce disulfide bonds in the protein, making its SH groups available for thioether bond formation. This approach offers advantages over traditional methods, as it can be performed under simple conditions without the need for an inert atmosphere or oxygen, and it avoids the formation of precipitates during the reaction.
Another significant patent is related to "Hepatotropic conjugates of antiviral drugs carriers thereof." This invention encompasses conjugated compounds of antiviral drugs with hepatotropic activity, detailing methods for their synthesis and compositions. These advancements are crucial for improving the delivery and effectiveness of antiviral therapies.
Career Highlights
Giuseppina has worked with notable organizations, including Laboratori Balducci S.p.a. and the University of Bologna. Her experience in these institutions has allowed her to collaborate on various research projects aimed at enhancing drug delivery systems.
Collaborations
Throughout her career, Giuseppina has collaborated with esteemed colleagues such as Luigi Fiume and Corrado Busi. These partnerships have contributed to her innovative research and the successful development of her patented technologies.
Conclusion
Giuseppina Di Stefano is a trailblazer in the field of pharmaceutical innovation, particularly in the area of antiviral drug conjugation. Her patents reflect her commitment to advancing medical science and improving patient outcomes through innovative drug delivery methods.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.