The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Dec. 11, 2020
Applicants:

Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;

Tes Pharma S.r.l., Perugia, IT;

Alma Mater Studiorum—universita' Di Bologna, Bologna, IT;

Istituto Europeo Di Oncologia S.r.l., Milan, IT;

Inventors:

Andrea Cavalli, Genoa, IT;

Domenico Milano, Genoa, IT;

Marcella Manerba, Genoa, IT;

Greta Bagnolini, Genoa, IT;

Jose Antonio Ortega Martinez, Genoa, IT;

Marinella Roberti, Bologna, IT;

Giuseppina Di Stefano, Bologna, IT;

Roberto Pellicciari, Perugia, IT;

Francesca De Franco, Perugia, IT;

Saverio Minucci, Perugia, IT;

Pier Giuseppe Pelicci, Milan, IT;

Viola Previtali, Genoa, IT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular for the use in the treatment of diseases or disorders wherein disrupting Rad51-BRCA2 interaction is beneficial.


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