Georgia Theofan

Title: Georgia Theofan: Innovator in Bactericidal Protein Products

Introduction

Georgia Theofan is a prominent inventor based in Torrance, California, known for her significant contributions to the field of bactericidal protein products. With a total of 12 patents to her name, she has made remarkable advancements in pharmaceutical compositions aimed at treating gram-negative bacterial infections.

Latest Patents

Among her latest patents is a groundbreaking invention titled "Stable bactericidal/permeability-increasing protein products and pharmaceutical compositions containing the same." This patent discloses novel bactericidal/permeability-increasing (BPI) protein products, wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or serine residue. Additionally, the leucine residue at position 193 is identified as the carboxy terminal residue. The patent also includes DNA sequences encoding methods for the production of these proteins in appropriate host cells, along with stable homogeneous pharmaceutical compositions containing the analogs suitable for treating gram-negative bacterial infections and their sequelae.

Career Highlights

Georgia has worked with notable companies in the biotechnology sector, including Xoma Corporation and International Genetic Engineering. Her work has significantly impacted the development of innovative treatments for bacterial infections.

Collaborations

Some of her notable coworkers include Lynn S. Grinna and Arnold H. Horwitz, who have collaborated with her on various projects throughout her career.

Conclusion

Georgia Theofan's contributions to the field of bactericidal protein products highlight her innovative spirit and dedication to advancing medical science. Her patents and collaborations continue to influence the development of effective treatments for bacterial infections.