The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2002
Filed:
Mar. 29, 1999
Applicant:
Inventors:
Héle{overscore (n)}e Gazzano-Santoro, San Bruno, CA (US);
Georgia Theofan, Torrance, CA (US);
Patrick W. Trown, Danville, CA (US);
Assignee:
Xoma Corporation, Berkeley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/816 ; C07K 1/400 ; C07H 2/104 ; C12N 1/511 ; C12N 1/563 ;
U.S. Cl.
CPC ...
A61K 3/816 ; C07K 1/400 ; C07H 2/104 ; C12N 1/511 ; C12N 1/563 ;
Abstract
Disclosed are novel biologically active lipopolysaccharide binding protein (LBP) derivatives including LBP derivative hybrid proteins which are characterized by the ability to bind to and neutralize LPS and which lack the CD14-mediated immunostimulatory properties of holo-LBP.