Company Filing History:
Years Active: 2021
Title: George O'Doherty: Innovator in Chemo-Enzymatic Modification
Introduction
George O'Doherty, based in Boston, MA, is an accomplished inventor known for his contributions to the field of biochemistry. With a focus on protein and peptide modifications, his innovative approach has led to the development of unique methods that enhance the capabilities of these biomolecules in therapeutic applications.
Latest Patents
O'Doherty holds one patent titled "Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates." This patent describes a method for reversibly modifying proteins or peptides at their glutamine residues. The technique involves a reaction, such as a transglutaminase-catalyzed reaction, where the peptide or protein is treated with an amine-containing reagent. The modification allows the linkage through the amine function to the glutamine's side chain, enabling the regeneration of the original protein or peptide form upon applying an appropriate stimulus.
Career Highlights
George O'Doherty is affiliated with Northeastern University, where he continues to push the boundaries of research in biochemistry and molecular biology. His work is crucial in advancing the understanding of protein modification, which has significant implications for drug development and delivery.
Collaborations
Throughout his career, O'Doherty has collaborated with talented colleagues such as Zhaohui Sunny Zhou and Shanshan Liu. Together, they explore innovative avenues in biochemical research, contributing valuable insights and advancements in their respective areas of expertise.
Conclusion
George O'Doherty stands out as a key figure in the realm of biochemical innovations. His patent on chemo-enzymatic modifications exemplifies the marriage of creativity and scientific inquiry, showcasing the potential for transformative advances in protein and peptide research. O'Doherty's contributions are not only paving the way for future discoveries but also significantly enhancing the therapeutic landscape.