This inventor holds 2 USPTO granted patents and 4 published patent applications, plus 1 CIPO patent and 1 EPO patent. Top assignees: Emisphere Technologies, Inc., Hoffmann-La Roche Inc.. Active years: 2009-2020.
Company Filing History:
2 out of 183 
1 out of 5,011 
Years Active: 2009-2020
Title: George Frederick Klein: Innovator in Pharmaceutical Synthesis
Introduction
George Frederick Klein is a notable inventor based in Tarrytown, NY (US). He has made significant contributions to the field of pharmaceutical synthesis, holding 2 patents that focus on improving methods for the manufacture of specific compounds.
Latest Patents
Klein's latest patents include a process for the manufacture of SNAC (salcaprozate sodium). This patent discloses improved methods for synthesizing N-(8-[2-hydroxybenzoyl]-amino) caprylic acid. Certain compounds have been identified as useful for preventing the formation of a colored impurity when included in an ester hydrolysis reaction. Conducting ester hydrolysis in anaerobic conditions has also been found to minimize the formation of this color impurity. Additionally, the patent outlines improved methods for synthesizing the sodium salt of N-(8-[2-hydroxybenzoyl]-amino) caprylic acid.
Career Highlights
Throughout his career, Klein has worked with prominent companies such as Emisphere Technologies, Inc. and Hoffmann-La Roche Inc. His work has significantly impacted the pharmaceutical industry, particularly in the synthesis of important compounds.
Collaborations
Klein has collaborated with notable individuals in his field, including Joseph Norman Bernadino and Yi Ren, who is a talented woman in the industry.
Conclusion
George Frederick Klein's innovative work in pharmaceutical synthesis has led to valuable advancements in the field. His patents reflect a commitment to improving manufacturing processes and enhancing the quality of pharmaceutical products.