George Bashirians

Title: Innovations and Contributions of George Bashirians

Introduction

George Bashirians is an accomplished inventor based in Penfield, NY (US). He has made significant contributions to the field of diagnostics, particularly in the area of angiogenic factors. With a total of 4 patents to his name, his work has the potential to impact various medical conditions.

Latest Patents

One of his latest patents is focused on the determination of the sFlt-1:angiogenic factor complex. This patent outlines methods for determining the presence or amount of a complex comprising a first and second molecular entity, specifically the sFlt-1:PlGF complex. The ability to determine this complex is crucial for predicting, detecting, and monitoring diseases such as vascular-related diseases, cardiac conditions, and preeclampsia. This innovation is particularly valuable for early detection of preeclampsia during gestation when clinical evaluations may not provide clear insights.

Another notable patent involves a calibrator/control for the simultaneous assay of proteins capable of complexing with one another. This patent discloses compositions and methods that include two or more proteins, with at least one protein altered to reduce mutual recognition and binding. These compositions serve as reference materials in assays for determining the presence of proteins in samples, specifically focusing on altered placental growth factor-1 (PlGF-1) and soluble fms-like tyrosine kinase (sFlt-1).

Career Highlights

George Bashirians is currently employed at Ortho-Clinical Diagnostics, Inc., where he continues to innovate in the field of medical diagnostics. His work is characterized by a commitment to improving disease detection and monitoring through advanced methodologies.

Collaborations

Throughout his career, George has collaborated with notable colleagues, including Jian Zheng and Deborah Byrne. These collaborations have contributed to the development of his innovative patents and have enhanced the impact of his work in the medical field.

Conclusion

George Bashirians exemplifies the spirit of innovation in medical diagnostics through his patents and contributions. His work not only advances scientific understanding but also holds the promise of improving patient outcomes in various diseases.