The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2014
Filed:
Jan. 07, 2009
George Bashirians, Penfield, NY (US);
Deborah Byrne, Rochester, NY (US);
Sarah Groulx, Ontario, NY (US);
Sharon Jackson, Rochester, NY (US);
Heather Lane-brown, Honeoye Falls, NY (US);
Banumathi Sankaran, Pittsford, NY (US);
Edward Scalice, Penfield, NY (US);
Karen Yang, Edison, NJ (US);
Jian Zheng, Raritan, NJ (US);
George Bashirians, Penfield, NY (US);
Deborah Byrne, Rochester, NY (US);
Sarah Groulx, Ontario, NY (US);
Sharon Jackson, Rochester, NY (US);
Heather Lane-Brown, Honeoye Falls, NY (US);
Banumathi Sankaran, Pittsford, NY (US);
Edward Scalice, Penfield, NY (US);
Karen Yang, Edison, NJ (US);
Jian Zheng, Raritan, NJ (US);
Ortho-Clinical Diagnostics, Inc., Raritan, NJ (US);
Abstract
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount of the complex can be used in methods for predicting, detecting, monitoring a disease, or guiding therapy in respect to a disease such as vascular, vascular-related disease, cardiac, cardiac-related disease, cancer, cancer-related disease, preeclampsia, and preeclampsia-related disease. Determining sFlt-1:angiogenic factor complex is particularly useful for predicting and detecting preeclampsia in early stages of gestation and in stages of the disease where clinical evaluation may be uninformative.