Location History:
- Sommerville, NJ (US) (2003)
- Somerville, NJ (US) (2010)
Company Filing History:
Years Active: 2003-2010
Title: The Innovative Contributions of George A. Keesler
Introduction
George A. Keesler, an accomplished inventor based in Sommerville, NJ, has made significant strides in the field of biochemistry and pharmaceuticals. With two patents to his name, Keesler's work focuses on the development of advanced methodologies and compounds that have the potential to revolutionize cellular delivery systems and circadian rhythm research.
Latest Patents
Keesler's latest innovations include two notable patents. The first patent revolves around membrane penetrating peptides and their uses. This invention is directed to the identification of membrane penetrating peptides that serve as intracellular delivery devices for compounds of interest, which can be utilized in vivo, ex vivo, and in vitro. The patent outlines methods for delivering specific compounds that are attached to these peptides to enhance cellular uptake.
The second patent relates to screening methods for altering circadian rhythms and human casein kinase I (CKI) phosphorylation of human clock proteins, including period 1, 2, and 3. This invention provides methods to identify test compounds that can alter the circadian rhythms of mammals. Moreover, it offers approaches to determine how these compounds selectively influence the phosphorylation and interactions of various human Period proteins.
Career Highlights
George A. Keesler works at Aventis Pharmaceuticals Inc., where he applies his expertise in biochemistry to advance pharmaceutical innovations. His research has the potential to enhance drug delivery systems and our understanding of biological timekeeping mechanisms.
Collaborations
Throughout his career, Keesler has collaborated with talented professionals, including Zhengbin Yao and Cesare Mondadori. These partnerships have enabled a multidisciplinary approach to research, further expanding the impact of their collective innovations.
Conclusion
George A. Keesler’s inventive contributions represent a significant advancement in the realms of cellular delivery and biological research. With his ongoing work at Aventis Pharmaceuticals Inc. and his collaborative efforts with esteemed colleagues, Keesler continues to drive innovation that may lead to groundbreaking developments in healthcare and biopharmaceuticals.