Company Filing History:
Years Active: 1993-2007
Title: The Innovative Contributions of Gavin D Dollinger
Introduction
Gavin D Dollinger is a notable inventor based in San Francisco, CA, with a focus on advancements in biochemistry and molecular biology. He holds 5 patents that reflect his innovative approach to solving complex scientific problems. His work has significantly contributed to the understanding of macromolecules and their interactions.
Latest Patents
One of Dollinger's latest patents is a method for determining the three-dimensional shape of a macromolecule. This invention provides a fast and efficient way to ascertain the three-dimensional conformation of proteins. The method involves several steps, including the formation of physical distance constraints through intramolecular chemical crosslinks, enriching the reaction pool, exposing it to a protease, measuring peptide fragment sizes, and interpreting the data to deduce spatial geometry and protein structure. The analysis is preferably supported by a computer system to generate and analyze distance constraints between amino acids.
Another significant patent is related to affinity selection of ligands by mass spectroscopy. This method allows for the rapid selection of compounds from a combinatorial library by contacting the library with a target receptor, separating non-binding compounds, and analyzing the resulting complexes through mass spectroscopy. This process enables the acquisition of structure-activity relationship (SAR) information by performing selections at varying ratios of compound to target.
Career Highlights
Dollinger has had a distinguished career, working with prominent companies such as Cetus Corporation and Chiron Corporation. His experience in these organizations has allowed him to develop and refine his innovative techniques in the field of biochemistry.
Collaborations
Throughout his career, Dollinger has collaborated with notable colleagues, including Robert L Cunico and Michael G Kunitani. These partnerships have fostered a collaborative environment that has led to significant advancements in their respective fields.
Conclusion
Gavin D Dollinger's contributions to the field of biochemistry through his innovative patents and collaborations highlight his role as a leading inventor. His work continues to influence the understanding of macromolecules and their applications in science and medicine.
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