Gary W Small

Title: The Innovative Contributions of Gary W. Small

Introduction

Gary W. Small is a prominent inventor based in Los Angeles, CA. He has made significant contributions to the field of medical imaging, particularly in the diagnosis and classification of neurological diseases. With a total of 5 patents to his name, Small's work has advanced the understanding of neurodegenerative conditions.

Latest Patents

One of his latest patents is a method for positron emission tomography (PET) imaging analysis for classifying and diagnosing neurological diseases. This innovative method utilizes PET images obtained with a radiotracer to determine the progressive course of regional brain PET activities in neurodegenerative diseases such as mild cognitive impairment (MCI), Alzheimer's disease (AD), and chronic traumatic encephalopathy (CTE). The technique allows for the automatic staging of these diseases based on regional intensity and spatial patterns of brain signals measured by PET imaging. Additionally, it aids in diagnosing or classifying a patient's disease among multiple possibilities based on PET imaging profiles, effectively distinguishing between conditions like CTE and AD.

Another notable patent involves in vivo imaging of sulfotransferases. This patent provides radiolabeled tracers for sulfotransferases (SULTs), detailing their synthesis and applications. It includes various substituted phenols, naphthols, coumarins, and flavones radiolabeled with isotopes. The patent also outlines in vivo techniques for using these tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity in both health and disease, as well as to evaluate therapeutic interventions.

Career Highlights

Gary W. Small is affiliated with the University of California, where he continues to contribute to research and innovation in medical imaging. His work has garnered attention for its potential impact on the early detection and treatment of neurological diseases.

Collaborations

Throughout his career, Small has collaborated with notable colleagues, including Jorge R. Barrio and Nagichettiar Satyamurthy. These collaborations have further enriched his research and expanded the scope of his inventions.

Conclusion

Gary W. Small's innovative contributions to medical imaging and neurodegenerative disease diagnosis highlight his importance in the field. His patents reflect a commitment to advancing healthcare through technology and research.