Waialua, HI, United States of America

Gary S Bignami


Average Co-Inventor Count = 2.5

ph-index = 2

Forward Citations = 47(Granted Patents)


Location History:

  • Waialua, HI (US) (1992 - 1994)
  • Honolulu, HI (US) (2002)

Company Filing History:


Years Active: 1992-2002

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3 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Gary S. Bignami

Introduction

Gary S. Bignami is a notable inventor based in Waialua, HI (US). He has made significant contributions to the field of biotechnology, particularly in vaccine development and purification processes. With a total of 3 patents to his name, Bignami's work has the potential to impact public health positively.

Latest Patents

One of his latest patents is a recombinant envelope vaccine against flavivirus infection. This vaccine contains at least one Drosophila cell-secreted, recombinantly-produced form of a truncated Flavivirus envelope glycoprotein as an active ingredient, along with an adjuvant that is crucial for its effectiveness. The adjuvant is an immunomodulating agent with an iscom-like structure, which includes at least one lipid and one saponin, combined with a pharmaceutically acceptable vehicle. This innovative vaccine aims to protect subjects from Flavivirus infections.

Another significant patent is the process for affinity purification by immunoadsorption in non-aqueous media. This method allows for immunoaffinity purifications using non-aqueous media, with the option of incorporating a small amount of an aqueous buffered medium and a surfactant. This technique enables the extraction of hydrophobic ligands from samples, leading to a substantially pure product.

Career Highlights

Gary S. Bignami is associated with Hawaii Biotechnology Group, Inc., where he continues to advance his research and development efforts. His work in the biotechnology sector has garnered attention for its innovative approaches to vaccine formulation and purification techniques.

Collaborations

Bignami has collaborated with notable colleagues, including Paul G. Grothaus and John M. Ivy. These partnerships have likely contributed to the success and development of his patented technologies.

Conclusion

In summary, Gary S. Bignami is a distinguished inventor whose work in biotechnology, particularly in vaccine development and purification processes, showcases his innovative spirit. His contributions are poised to make a significant impact in the field of public health.

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