The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2002
Filed:
Jul. 13, 1999
Applicant:
Inventors:
John Ivy, College Station, TX (US);
Gary Bignami, Honolulu, HI (US);
Michael McDonell, Bogart, GA (US);
David E. Clements, Honolulu, HI (US);
Beth-Ann G. Coller, Woluwe Saint Lambert, BE;
Assignee:
Hawaii Biotechnology Group, Aiea, HI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ;
U.S. Cl.
CPC ...
A61K 3/912 ;
Abstract
A vaccine contains at least one Drosophila cell-secreted, recombinantly-produced form of a truncated Flavivirus envelope glycoprotein, as an active ingredient, and an adjuvant, as a critical component of the vaccine. The adjuvant is an immunomodulating agent having an iscom-like structure and comprising within the iscom-like structure at least one lipid and at least one saponin, and a pharmaceutically acceptable vehicle. Such a vaccine protects a subject against infection by a Flavivirus.