David Edward Clements

Title: David Edward Clements: Innovator in Biotechnology

Introduction

David Edward Clements is a prominent inventor based in Honolulu, HI (US). He has made significant contributions to the field of biotechnology, particularly in the development of vaccines. With a total of 10 patents to his name, Clements has focused on addressing critical health challenges through innovative solutions.

Latest Patents

Among his latest patents is the invention titled "Optimized Zika virus envelope gene and expression thereof." This invention is directed to the expression and secretion of the Zika virus envelope protein. Elements of the pre-membrane and envelope sequence have been modified to enhance the expression of the envelope protein as a secreted product in the culture medium of transformed insect cell lines. The expressed and purified product is suitable as a vaccine antigen. Another notable patent is the "West Nile virus vaccine and method of use thereof." This patent describes a West Nile virus (WNV) vaccine for human use that contains a recombinantly produced form of truncated WNV envelope glycoprotein and a combination of a Toll-like receptor 4 (TLR-4) and saponin adjuvants. A pharmaceutically acceptable vehicle may also be included in the vaccine.

Career Highlights

Clements has worked with several companies in the biotechnology sector, including Hawaii Biotechnology Group, Inc. and Hawaii Biotech, Inc. His work has been instrumental in advancing vaccine development and addressing viral infections.

Collaborations

Throughout his career, Clements has collaborated with notable individuals in the field, including John M Ivy and Eilen Nakano. These collaborations have contributed to the success of his innovative projects.

Conclusion

David Edward Clements is a key figure in the biotechnology industry, known for his innovative patents and contributions to vaccine development. His work continues to impact public health positively.