Company Filing History:
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Years Active: 2005-2023
Title: Innovations and Contributions of Gary R Matyas
Introduction
Gary R Matyas is a notable inventor based in Olney, MD (US), recognized for his significant contributions to the field of pharmaceutical compositions and vaccine delivery. With a total of six patents to his name, Matyas has made strides in developing innovative solutions for complex medical challenges.
Latest Patents
Among his latest patents, Matyas has developed recombinant circumsporozoite protein compositions and methods for vaccine delivery. This invention relates to pharmaceutical compositions that include at least one antigen and an adjuvant composition. The adjuvant composition comprises a saponin and a liposome, where the liposome contains monophosphoryl lipid A (MPLA), cholesterol, and a phospholipid that remains in a liquid crystalline state at temperatures greater than or equal to 23°C. The concentration of cholesterol to lipid in the liposome exceeds 50% (mol/mol). The antigen in this composition is a soluble recombinant circumsporozoite protein (rCSP) that includes the amino acid sequence of SEQ ID NO:1 or an rCSP peptide that is at least 95% identical to this sequence. Additionally, he has worked on truncated HIV envelope proteins, providing methods and compositions related to novel HIV envelope proteins, which are suitable for use as vaccines against HIV.
Career Highlights
Matyas has had a distinguished career, working with organizations such as the U.S. Government, represented by the Secretary of the Army, and the Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. His work has been pivotal in advancing medical research and developing effective vaccine strategies.
Collaborations
Throughout his career, Matyas has collaborated with esteemed colleagues, including Carl R Alving and Mangala Rao. These partnerships have contributed to the success of his innovative projects and research endeavors.
Conclusion
Gary R Matyas stands out as a prominent inventor whose work in vaccine development and pharmaceutical compositions has the potential to impact public health significantly. His innovative patents and collaborations reflect his commitment to advancing medical science and improving health outcomes.