Company Filing History:
Years Active: 1997-1999
Title: Gary Kent McMaster: Innovator in Protein Refolding Technology
Introduction
Gary Kent McMaster, an accomplished inventor based in Kaiseraugst, Switzerland, has made significant contributions to the field of biotechnology. With two patents to his name, he has focused primarily on the development of biologically active proteins, particularly Transforming Growth Factor beta (TGF-β), which plays a crucial role in various therapeutic applications.
Latest Patents
Among McMaster's latest innovations is a patented process for refolding recombinantly produced TGF-β-like proteins. This patented process pertains to producing biologically active, dimeric forms of TGF-β from denatured monomeric proteins, utilizing mild detergents to facilitate proper folding. The dimerized TGF-β exhibits significant therapeutic potential, including applications in wound healing, bone and tissue repair, cancer treatment, and as a growth regulator in cell cultures. Additionally, the invention emphasizes the importance of maintaining protein solubility during the refolding process, ensuring a stable and active product.
Career Highlights
McMaster's professional journey includes notable tenures at leading pharmaceutical companies such as Ciba-Geigy Corporation and Novartis Corporation. His work in these organizations has propelled advancements in the production and application of therapeutic proteins, shaping modern biopharmaceutical practices.
Collaborations
Throughout his career, McMaster has collaborated with esteemed colleagues, including Nico Cerletti and David Cox. These partnerships have facilitated innovative research and development, enhancing the efficacy of biotechnological solutions in clinical settings.
Conclusion
Gary Kent McMaster's contributions to the field of biotechnology, particularly through his patented processes for producing biologically active proteins, underscore the significance of innovation in healthcare. His work not only advances scientific understanding but also paves the way for transformative therapeutic options in various medical fields. As he continues to push the boundaries of protein technology, McMaster exemplifies the spirit of innovation that drives the biopharmaceutical industry forward.