Location History:
- Lexington, MA (US) (1999)
- Atlanta, GA (US) (2003)
- Palo Alto, CA (US) (1995 - 2004)
Company Filing History:
9 out of 5,309 
2 out of 1,373 
Years Active: 1995-2004
Title: Gary H Gibbons: Innovator in Therapeutic Applications of Oligodeoxynucleotide Decoys
Introduction
Gary H Gibbons is a prominent inventor based in Palo Alto, CA (US). He has made significant contributions to the field of therapeutic treatments, holding a total of 11 patents. His work primarily focuses on the use of oligodeoxynucleotide decoys for the treatment of various diseases.
Latest Patents
One of Gibbons' latest patents is centered on the therapeutic use of cis-element decoys in vivo. This invention provides a method for using oligodeoxynucleotide decoys to treat diseases linked to the binding of endogenous transcription factors to genes involved in cell growth, differentiation, and signaling, as well as to viral genes. By inhibiting these trans-activating factors from binding to transcription regulatory regions, the decoys can modulate gene expression. This modulation helps regulate pathological processes such as inflammation, intimal hyperplasia, angiogenesis, neoplasia, immune responses, and viral infections. The decoys are administered in specific amounts and conditions to effectively inhibit the binding of endogenous transcription factors to their respective genes without causing significant host toxicity. The compositions include decoy molecules designed for optimal pharmacokinetics to ensure effective therapeutic use.
Career Highlights
Throughout his career, Gary H Gibbons has worked with esteemed institutions, including Leland Stanford Junior University and The Brigham and Women's Hospital, Inc. His innovative research has paved the way for advancements in therapeutic applications.
Collaborations
Gibbons has collaborated with notable professionals in his field, including Victor J Dzau and John P Cooke. Their combined expertise has contributed to the success of his research and inventions.
Conclusion
Gary H Gibbons stands out as a key figure in the development of therapeutic strategies using oligodeoxynucleotide decoys. His innovative work continues to impact the medical field significantly.