This inventor holds 2 USPTO granted patents. Top assignee: Wyeth. Active years: 2009.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2009
Title: G Roger Askew: Innovator in Gene Targeting and Bone Mass Modulation
Introduction
G Roger Askew is a notable inventor based in Boxford, MA (US). He has made significant contributions to the fields of gene targeting and bone mass modulation. With a total of 2 patents, his work has implications for genetic research and medical treatments.
Latest Patents
G Roger Askew's latest patents include a "Conditional knockout method for gene trapping and gene targeting using an inducible gene silencer." This method allows for the conditional alteration of gene function and genetic sequences, which can be utilized in gene trapping and gene targeting. The invention features a genetic sequence that includes a splice acceptor sequence, an internal ribosomal entry site (IRES) sequence, a nucleotide sequence coding for a reporter protein, a polyadenylation sequence, and a pair of oppositely oriented recombination site sequences. These elements facilitate single cycle inversions in the presence of a suitable recombinase enzyme.
Another significant patent is the "Transgenic animal model of bone mass modulation." This invention relates to methods and materials for expressing the HBM protein in animal cells and transgenic animals. It also encompasses transgenic animals that express the high bone mass gene, the corresponding wild-type gene, and mutants thereof. The invention provides nucleic acids, proteins, cloning vectors, and methods for developing pharmaceutical compositions aimed at diagnosing and treating diseases related to bone development, particularly osteoporosis.
Career Highlights
G Roger Askew has been associated with Wyeth, where he has contributed to groundbreaking research in genetics and pharmaceuticals. His work has paved the way for advancements in gene therapy and treatments for bone-related diseases.
Collaborations
Throughout his career, G Roger Askew has collaborated with notable colleagues, including Philip Babij and Frederick James Bex, III. These collaborations have enhanced the scope and impact of his research.
Conclusion
G Roger Askew's innovative work in gene targeting and bone mass modulation has made a significant impact in the field of genetics. His patents reflect a commitment to advancing medical science and improving treatment options for various conditions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile