The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7625755 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 01, 2009

Filed:

May. 30, 2003
Applicants:

G. Roger Askew, Boxford, MA (US);

Kim L. Kanki, Boxford, MA (US);

Inventors:

G. Roger Askew, Boxford, MA (US);

Kim L. Kanki, Boxford, MA (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for conditionally knocking out and altering gene function and genetic sequences that can be used in such methods, for use in gene trapping and gene targeting. Specifically, the genetic sequence is a inducible gene silencer comprising: (a) a splice acceptor sequence; (b) an internal ribosomal entry site (IRES) sequence; (c) a nucleotide sequence coding for a reporter protein; (d) a polyadenylation sequence; and (e) a pair of oppositely oriented recombination site sequences, which cause single cycle inversions in the presence of a suitable recombinase enzyme, flanking elements (a) through (d).


Find Patent Forward Citations

Askew, G.. (2009). Conditional knockout method for gene trapping and gene targeting using an inducible gene silencer (U.S. Patent No. 7625755). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7625755

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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