G Marc Loudon

Title: G Marc Loudon: Innovator in Protein Sequencing

Introduction

G Marc Loudon is a notable inventor based in West Lafayette, IN (US). He has made significant contributions to the field of protein sequencing, particularly through his innovative methods that enhance the accuracy and efficiency of C-terminal sequencing.

Latest Patents

Loudon's most recent patent is titled "Acetic anhydride activation for C-terminal protein sequencing." This patent describes a method for C-terminal sequencing of proteins or peptides. A key feature of this method is the formation of an oxazolone moiety at the C-terminus of a protein or peptide by treatment with acetic anhydride under basic conditions. This is followed by the conversion of the oxazolone to a thiohydantoin moiety through treatment with thiocyanate under acidic conditions. The yields of thiohydantoin are further enhanced by delivering thiocyanate as the conjugate acid of a sterically hindered alkylammonium cation. Loudon holds 1 patent for this innovative technique.

Career Highlights

G Marc Loudon is associated with The Perkin-Elmer Corporation, where he has been able to apply his expertise in protein chemistry. His work has contributed to advancements in biochemical research and applications.

Collaborations

Loudon has collaborated with notable colleagues, including MeriLisa Bozzini and Victoria L Boyd, who have also contributed to the field of protein sequencing.

Conclusion

G Marc Loudon's innovative work in protein sequencing exemplifies the impact of scientific research on biochemistry. His patented methods continue to influence the way proteins are analyzed and understood.