Ottawa, Canada

G Dennis Sprott



 

Average Co-Inventor Count = 3.4

ph-index = 3

Forward Citations = 25(Granted Patents)


Location History:

  • Orleans, CA (2000 - 2002)
  • Ottawa, CA (1999 - 2020)

Company Filing History:


Years Active: 1999-2020

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4 patents (USPTO):Explore Patents

Title: G Dennis Sprott: Innovator in Vaccine Adjuvants

Introduction

G Dennis Sprott is a notable inventor based in Ottawa, Canada. He has made significant contributions to the field of immunology, particularly in the development of novel vaccine adjuvants. With a total of 4 patents, his work focuses on enhancing immune responses through innovative formulations.

Latest Patents

One of his latest patents involves sulfated-glycolipids as adjuvants for vaccines. This patent describes a synthetic charged glycolipid that comprises a sulfated saccharide group covalently linked to the sn-1 hydroxyl group of the glycerol backbone of an archaeal core lipid via a beta linkage. The synthetic charged glycolipids include compounds of formula I, wherein n is 0 or 1; R is hydrogen or hydroxyl; and Y is hydrogen or a sulfate group, with at least one Y being a sulfate group. These sulfated glycolipids produce stable archaeosomes at a mol % ratio ranging from 100:0 to 30:70, which induce a protective immune response, including CD8 and CD4 T cell responses. Another significant patent focuses on archaeosomes containing coenzyme Q10 and other types of liposomes as adjuvants and delivery vehicles. These novel archaeosome compositions enhance the immune response to immunogens and improve the delivery of pharmaceuticals to specific cell types and tissues.

Career Highlights

G Dennis Sprott is affiliated with the National Research Council of Canada, where he continues to advance research in vaccine development. His innovative approaches have positioned him as a key figure in the field of immunology.

Collaborations

He has collaborated with notable colleagues, including Girishchandra Babubhai Patel and Boby Makabi-Panzu, who contribute to his research endeavors.

Conclusion

G Dennis Sprott's work in vaccine adjuvants and delivery systems showcases his commitment to enhancing immunological responses. His innovative patents and collaborations reflect his significant impact on the field of immunology.

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