Füsûn N Zeytin

Title: Füsûn N Zeytin: Innovator in Botulinum Toxin Research

Introduction

Füsûn N Zeytin is a prominent inventor based in Del Mar, California. He has made significant contributions to the field of botulinum toxin research, holding 2 patents that focus on innovative methods for analyzing and inhibiting botulinum protease activity.

Latest Patents

His latest patents include "Resonance energy transfer assay with synaptobrevin substrate moiety" and "Thiazoline ring compounds as botulinum antagonists." The first patent provides compositions and methods for analyzing intracellular BoNT protease activity, particularly for BoNT/B, BoNT/G, BoNT/D, and/or BoNT/F. This method involves cells expressing recombinant hybrid proteins that include fluorescent proteins and BoNT protease recognition sequences, with analysis performed using FRET analysis. The second patent presents compositions and methods for inhibiting BoNT protease activity, featuring inhibitors that comprise various reactive groups and rings, such as isothiazolone and thiadiazolidine dione, which effectively inhibit BoNT/A at micromolar and sub-micromolar concentrations.

Career Highlights

Füsûn N Zeytin is associated with Biomadison, Inc., where he continues to advance research in the field of botulinum toxins. His work has been instrumental in developing new methodologies that enhance the understanding and treatment of botulinum toxin-related conditions.

Collaborations

He collaborates with Ward C Tucker, contributing to the innovative research environment at Biomadison, Inc. Their combined expertise fosters advancements in the field.

Conclusion

Füsûn N Zeytin's contributions to botulinum toxin research through his patents and collaborations highlight his role as a key innovator in this specialized field. His work continues to pave the way for new therapeutic approaches and methodologies.