The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Oct. 15, 2010
Applicants:
Ward C. Tucker, Monona, WI (US);
Füsûn N. Zeytin, Del Mar, CA (US);
Inventors:
Ward C. Tucker, Monona, WI (US);
Füsûn N. Zeytin, Del Mar, CA (US);
Assignee:
BIOMADISON, INC., Del Mar, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/37 (2013.01); C07K 2319/50 (2013.01); C07K 2319/60 (2013.01); G01N 2333/96486 (2013.01);
Abstract
Compositions and methods for analyzing intracellular BoNT protease activity, and especially BoNT/B, BoNT/G, BoNT/D, and/or BoNT/F protease activity are provided. Most preferably, cells express one or more recombinant hybrid proteins that include one or more fluorescent proteins and at least one BoNT protease recognition and cleavage sequence, and analysis is performed using FRET analysis.