Iruma-gun, Japan

Fuminori Ohba


Average Co-Inventor Count = 11.0

ph-index = 1

Forward Citations = 4(Granted Patents)


Company Filing History:


Years Active: 2008-2011

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6 patents (USPTO):Explore Patents

Title: Fuminori Ohba: Innovator in Fungal Cell Wall Synthesis

Introduction

Fuminori Ohba is a notable inventor based in Iruma-gun, Japan. He has made significant contributions to the field of fungal biology, particularly in understanding and manipulating fungal cell wall synthesis. With a total of 6 patents to his name, his work has implications for developing novel antifungal agents.

Latest Patents

Ohba's latest patents focus on the synthesis of fungal cell wall components. One of his key inventions involves isolated DNA encoding a GWT1 protein, which plays a crucial role in conferring resistance to fungi against specific compounds. A defect in the GWT1 protein function results in a reduced amount of glycosylphosphatidylinositol (GPI)-anchored proteins in the fungal cell wall. Additionally, he developed a reporter system that reflects the transport process of GPI-anchored proteins to the cell wall. This system has led to the discovery of compounds that inhibit this transport process. Furthermore, he identified fungal genes that confer resistance to these compounds and developed methods for screening inhibitors of the proteins encoded by these genes. His innovative approach suggests that antifungal agents with a novel mechanism can be achieved by inhibiting the transport of GPI-anchored proteins to the cell wall.

Career Highlights

Fuminori Ohba has worked with prominent companies in the pharmaceutical industry, including Eisai R&D Management Co., Ltd. and Eisai Company, Limited. His experience in these organizations has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Ohba has collaborated with notable colleagues such as Kappei Tsukahara and Katsura Hata. Their combined expertise has further advanced the understanding of fungal biology and the development of new therapeutic strategies.

Conclusion

Fuminori Ohba's innovative work in fungal cell wall synthesis has the potential to revolutionize antifungal treatments. His patents and collaborations highlight his significant contributions to the field, making him a key figure in the ongoing battle against fungal infections.

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