Company Filing History:
Years Active: 1996-1997
Title: Innovations by Friedhelm L. Brinkhaus in Biosynthesis
Introduction
Friedhelm L. Brinkhaus is a distinguished inventor based in Lisle, IL, recognized for his contributions to the field of biosynthesis. With a total of six patents to his name, Brinkhaus has made significant strides in the area of genetic engineering and enzyme production, particularly focusing on the biosynthesis of compounds such as zeaxanthin and beta-carotene.
Latest Patents
Brinkhaus's latest patents involve innovative methods and genetic constructs that enhance the biosynthesis of zeaxanthin and glycosylated zeaxanthin through recombinant DNA technology. His research details the use of DNA segments encoding enzymes from Erwinia herbicola, including geranylgeranyl pyrophosphate (GGPP) synthase, phytoene synthase, phytoene dehydrogenase-4H, lycopene cyclase, beta-carotene hydroxylase, and zeaxanthin glycosylase. These patents cover not only the production of zeaxanthin and zeaxanthin diglucoside in transformed host organisms but also include DNA variants and analogs that exhibit similar enzymatic activity. Additionally, he has developed methods for beta-carotene biosynthesis using genetically engineered hosts, further advancing the potential applications of these enzymes in biotechnology.
Career Highlights
Friedhelm L. Brinkhaus has dedicated his career to advancing the field of biotechnology while working at Amoco Corporation. His innovative research has not only led to a series of patents but has also paved the way for future advancements in the area of genetic engineering, contributing to the production of valuable biochemical compounds.
Collaborations
Throughout his career, Brinkhaus has collaborated with esteemed colleagues such as Rodney L. Ausich and Indrani Mukharji. These collaborations have fostered an environment of innovation and discovery, enabling the successful development of new technologies and methods in biosynthesis.
Conclusion
Friedhelm L. Brinkhaus exemplifies the spirit of innovation present in the biotechnology industry. With an impressive portfolio of patents focused on the biosynthesis of key compounds, he has made a lasting impact on the field. As research continues to evolve, Brinkhaus’s pioneering work will undoubtedly influence future endeavors in the area of genetic engineering and biotechnology.