Fredrick H Brohn

Title: Fredrick H. Brohn: Innovator in Trypanosomiasis Control

Introduction

Fredrick H. Brohn is a notable inventor based in New York, NY (US). He has made significant contributions to the field of medical science, particularly in the control of trypanosomiasis, a disease caused by parasitic protozoa.

Latest Patents

Brohn holds a patent for a method aimed at controlling trypanosomiasis. The patent describes a composition that includes from 0.02 to 17 parts by weight of glycerol per part by weight of an iron chelating agent. This agent is selected from a group that includes salicyl hydroxyamic acid, 2,3- and 3,4-dihydroxy benzoic acid, and halobenzohydroxamic acids. When administered parenterally, this composition effectively blocks both aerobic and anaerobic glucose catabolism, thereby controlling several trypanosomes, including Trypanosoma brucei, T. gambiense, T. rhodesiense, T. equiperdum, T. evansi, T. congolense, and T. vivax. The therapeutic dosage for mammals is calculated to provide at least 138 mg/kg of body weight of glycerol and at least 96 mg/kg of body weight of the iron chelating agent.

Career Highlights

Fredrick H. Brohn is affiliated with The Rockefeller University, where he conducts his research and development work. His innovative approach to treating trypanosomiasis has garnered attention in the scientific community.

Collaborations

One of his notable collaborators is Allen B. Clarkson, Jr., with whom he has worked closely on various research projects.

Conclusion

Fredrick H. Brohn's contributions to the field of medical science, particularly in the control of trypanosomiasis, highlight his innovative spirit and dedication to improving health outcomes. His work continues to influence research in this critical area.