Company Filing History:
10 out of 1,153 
1 out of 92 
Years Active: 2000-2021
Title: The Innovations of Frederick R. Haselton
Introduction
Frederick R. Haselton is a notable inventor based in Nashville, TN (US), recognized for his contributions to the field of molecular diagnostics. With a total of 10 patents, Haselton has made significant advancements in the monitoring and analysis of nucleic acids, which are crucial for various biological and medical applications.
Latest Patents
One of Haselton's latest patents focuses on the monitoring and analysis of nucleic acid hybridization state and amplification using L-DNA. This invention describes systems, methods, and compositions for monitoring and analyzing nucleic acid hybridization states using L-DNA probes. The methods involve adding L-DNA probes that can be fluorescently detected to a system that includes D-DNA. These probes consist of primer, target, and antisense nucleotide sequences, along with fluorescent dye compounds. They are particularly useful for monitoring and analyzing various parameters during DNA amplification using the polymerase chain reaction.
Another significant patent by Haselton involves liquid diagnostic assays utilizing marangoni flow. This invention provides simple and inexpensive assays for detecting virtually any analyte in liquid samples or those that can be solubilized. The assays leverage the fluid dynamics of drop evaporation, where soluble materials, including analytes and particles binding to them, are drawn to the center of the drop by Marangoni flow, ultimately forming a concentrated residual spot. The presence or absence of certain reagents can then be detected through various approaches.
Career Highlights
Throughout his career, Haselton has worked with esteemed organizations such as Vanderbilt University and Bioventures, LLC. His work has significantly impacted the field of diagnostics, particularly in developing innovative methods for analyzing nucleic acids.
Collaborations
Haselton has collaborated with notable individuals in his field, including John P. Wikswo and Franz Baudenbacher. These collaborations have further enhanced his research and contributions to molecular diagnostics.
Conclusion
Frederick R. Haselton's innovative work in the field of molecular diagnostics has led to significant advancements in the monitoring and analysis of nucleic acids. His patents reflect a commitment to improving diagnostic methods, which can have a profound impact on medical research and applications.