This inventor holds 3 USPTO granted patents. Top assignees: Bio-Rad Laboratories, Inc., Digilab, LLC. Active years: 1999-2003.
Company Filing History:
Years Active: 1999-2003
Title: Innovations by Frederick R Cahn in Cervical Cancer Detection
Introduction
Frederick R Cahn is an accomplished inventor based in Princeton, NJ (US). He has made significant contributions to the field of medical diagnostics, particularly in the detection of cervical cancer. With a total of 3 patents, his work focuses on utilizing advanced spectroscopic techniques to identify cellular abnormalities associated with disease states.
Latest Patents
One of Cahn's notable inventions is a method for the detection of cellular abnormalities using Fourier transform infrared spectroscopy. This innovative approach teaches a method to identify cellular abnormalities linked to disease states by utilizing infrared (IR) spectra of cell samples. The samples are dried on an infrared-transparent matrix and scanned within a frequency range from 3000-950 cm. The identification process is based on establishing a reference using a representative set of spectra from normal and diseased specimens. Multivariate techniques such as Principal Component Analysis (PCA) and Partial Least Squares (PLS) are employed to reduce data based on maximum variations between the spectra. This method allows for the reliable distinction between normal, dysplastic, and malignant cervical smears.
Another significant patent by Cahn is a method for detecting malignant and premalignant stages of cervical cancer. This invention also utilizes IR spectra of exfoliated cervical cells, dried on an infrared transparent matrix, and scanned at the same frequency range. The calibration process for this method similarly employs PCA and PLS to achieve statistically reliable distinctions among different groups of cervical smears.
Career Highlights
Throughout his career, Frederick R Cahn has worked with prominent companies such as Bio-Rad Laboratories, Inc. and Digilab, LLC. His experience in these organizations has contributed to his expertise in the field of medical diagnostics and innovation.
Collaborations
Cahn has collaborated with notable individuals in his field, including Krishnaswamy Krishnan and Menashi A Cohenford. These collaborations have likely enhanced the development and application of his innovative methods.
Conclusion
Frederick R Cahn's contributions to the detection of cervical cancer through innovative spectroscopic methods highlight his significant role as an inventor. His work not only advances medical diagnostics but also has the potential to improve patient outcomes in the fight against cervical cancer.