This inventor holds 4 USPTO granted patents. Top assignees: The United States of America, The United States of America as Represented by the Department of Health, The United States of America as Represented by the Secretary of. Active years: 1992-1999.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Baltimore, MD (US) (1992 - 1997)
- Riehen, CH (1999)
Company Filing History:
2 out of 255 
1 out of 1,217 
1 out of 2,202 
Years Active: 1992-1999
Title: Frederick J Monsma, Jr: Innovator in Dopamine Receptor Research
Introduction
Frederick J Monsma, Jr is a notable inventor based in Baltimore, MD (US). He has made significant contributions to the field of molecular biology, particularly in the study of dopamine receptors. With a total of 4 patents to his name, Monsma has been instrumental in advancing our understanding of receptor biology.
Latest Patents
Monsma's latest patent focuses on the PCT-65 serotonin receptor and the cDNA encoding a rat D.sub.1 dopamine receptor linked to adenylyl cyclase. This invention relates to the molecular cloning and expression of the D.sub.1 dopamine receptor protein, which is crucial for the activation of adenylyl cyclase activity. By constructing cell lines that express the D.sub.1 receptor, researchers can assess the affinities and efficacies of various agonist and antagonist drugs. The invention also includes a recombinant DNA construct that features a vector and a DNA fragment encoding the D.sub.1 receptor. Furthermore, it describes a host cell transformed with this recombinant DNA construct, allowing for the expression and production of the D.sub.1 receptor. Suitable expression systems for this invention include both eukaryotic and prokaryotic cells, particularly mammalian cells such as rat or human. Additionally, the invention encompasses antibodies to the D.sub.1 receptor protein, which can be prepared for diagnostic purposes.
Career Highlights
Monsma has worked with various organizations, including the United States of America and its Secretary. His work has significantly impacted the field of receptor research, leading to advancements in understanding dopamine receptor functions.
Collaborations
Monsma has collaborated with notable individuals in his field, including David Robert Sibley and Loris D McVittie. These collaborations have further enriched his research and contributions to receptor biology.
Conclusion
Frederick J Monsma, Jr is a distinguished inventor whose work in dopamine receptor research has led to important advancements in molecular biology. His patents and collaborations reflect his commitment to innovation in this critical area of study.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile