Frans Van Wijnendaele

Title: The Innovative Contributions of Frans Van Wijnendaele

Introduction

Frans Van Wijnendaele is a notable inventor based in Ottenburg, Belgium. He has made significant contributions to the field of protein extraction and purification, holding a total of 3 patents. His work has implications in biotechnology and medical research, particularly in the area of vaccine development.

Latest Patents

Frans Van Wijnendaele's latest patents include a process for the extraction and purification of proteins from culture. This process is applicable to the supernatant of engineered yeast cells disrupted in the presence of a non-ionic detergent. It involves the precipitation of contaminants by polyethylene glycol and subsequent treatment with cation or ammonium sulfate after ultrafiltration. Another significant patent is the method for the isolation and purification of hepatitis B surface antigen. In this method, the supernatant of engineered yeast cells producing hepatitis B surface antigen is clarified by the addition of urea and adsorbed on colloidal silica. The purified antigen is then desorbed using a low ionic strength buffer supplemented with urea and a non-ionic detergent.

Career Highlights

Throughout his career, Frans has worked with reputable companies such as Smith Kline Rit and SmithKline-Rit. His expertise in protein purification has been instrumental in advancing research in various biotechnological applications.

Collaborations

Frans has collaborated with notable professionals in his field, including Guy Simonet and Daniel Gilles. Their combined efforts have contributed to the successful development of innovative processes in protein extraction.

Conclusion

Frans Van Wijnendaele's contributions to the field of biotechnology through his patents and collaborations highlight his role as a significant inventor. His work continues to influence advancements in protein purification and medical research.