Location History:
- New York, NY (US) (2002 - 2006)
- Katonah, NY (US) (2010)
Company Filing History:
2 out of 5,182 
1 out of 7 
1 out of 41 Years Active: 2002-2010
Title: Frank Traganos: Innovator in Tobacco Research and Cellular Analysis
Introduction
Frank Traganos is a notable inventor based in Katonah, NY (US). He has made significant contributions to the fields of tobacco research and cellular analysis. With a total of 4 patents to his name, Traganos has focused on developing methods that enhance the understanding of tobacco-related diseases and cellular behavior.
Latest Patents
Traganos's latest patents include innovative approaches to identify less harmful tobacco and tobacco products. This invention concerns methods for detecting, identifying, and evaluating tobacco and tobacco products to determine their potential contribution to tobacco-related diseases. It is based on the discovery that exposure of pulmonary cells to smoke or smoke condensate from tobacco products induces double-stranded breaks in cellular DNA. These breaks can be efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX.
Another significant patent involves the detection of protein conformations in single cells. This patent provides methods, reagents, and kits that allow for flow cytometric determination of the phosphorylation status of the retinoblastoma susceptibility gene protein (pRB) in individual cells. The methods enable the measurement of the hypophosphorylated, active form of pRB, either as an absolute quantity or as a proportion of total cellular pRB. Additionally, these methods correlate pRB phosphorylation status with cell cycle phase and protein components of the cell cycle.
Career Highlights
Throughout his career, Frank Traganos has worked with prominent companies such as Becton Dickinson and Company Limited and Vector Tobacco Inc. His work has significantly impacted the understanding of tobacco products and their effects on human health.
Collaborations
Traganos has collaborated with notable individuals in his field, including Zbigniew Darzynkiewicz and Gloria Juan. These collaborations have furthered his research and contributed to the development of innovative solutions in tobacco research and cellular analysis.
Conclusion
Frank Traganos is a distinguished inventor whose work has advanced the understanding of tobacco-related diseases and cellular behavior. His contributions through patents and collaborations highlight his commitment to innovation in these critical areas.