The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
May. 11, 2005
Anthony P. Albino, New York, NY (US);
Ellen D. Jorgensen, South Salem, NY (US);
Frank Traganos, Katonah, NY (US);
Zbigniew Darzynkiewicz, Chappaque, NY (US);
Wendy Jin, Chapel Hill, NC (US);
Anthony P. Albino, New York, NY (US);
Ellen D. Jorgensen, South Salem, NY (US);
Frank Traganos, Katonah, NY (US);
Zbigniew Darzynkiewicz, Chappaque, NY (US);
Wendy Jin, Chapel Hill, NC (US);
Vector Tobacco, Inc., Morrisville, NC (US);
Abstract
Aspects of the invention concern methods for detecting, identifying and evaluating tobacco and tobacco products to determine the potential that these compositions have to contribute to a tobacco-related disease. It is based, at least in part; on the discovery that exposure of pulmonary cells to smoke or smoke condensate obtained from tobacco or tobacco products induces double stranded breaks in cellular DNA, which were efficiently detected using assays that measure the presence, absence, or amount of phosphorylation of the histone, H2AX.