This inventor holds 7 USPTO granted patents and 9 published patent applications and 5 EPO patents. Top assignees: Technische Universitát Dresden, Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E. V. , Heinrich-Pette-Institut Für Experimentelle Virologie Und Immunologie an Der Universität Hamburg. Active years: 2014-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:


Years Active: 2014-2023
Title: Frank Buchholz: Innovator in Genetic Engineering
Introduction
Frank Buchholz is a prominent inventor based in Dresden, Germany. He has made significant contributions to the field of genetic engineering, holding a total of 7 patents. His work focuses on innovative methods for genome editing and the development of tailored recombinases.
Latest Patents
One of his latest patents is titled "Methods and means for genetic alteration of genomes utilizing designer DNA recombining enzymes." This invention provides methods for specifically altering DNA sequences in a genome, particularly for genome editing by deleting or replacing sequences of interest. The invention is particularly useful in medicine, allowing for the repair of mutations in genomes or the deletion of predefined genetic material from cells or tissues to cure diseases. A key advantage of this invention is its ability to enable precise site-directed alterations of DNA without engaging host DNA repair pathways, thus avoiding random insertions and deletions.
Another notable patent is "Tailored recombinase for recombining asymmetric target sites in a plurality of retrovirus strains." This invention relates to a method for preparing an expression vector that encodes a tailored recombinase capable of recombining asymmetric target sequences within the long terminal repeat (LTR) of proviral DNA of various retrovirus strains. This technology is particularly relevant for the treatment and prevention of retrovirus infections, including those caused by multiple strains of HIV.
Career Highlights
Frank Buchholz has worked with esteemed institutions such as Technische Universität Dresden and the Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. His research has significantly advanced the understanding and application of genetic engineering techniques.
Collaborations
Throughout his career, Buchholz has collaborated with notable colleagues, including Joachim Hauber and Madina Karimova. These partnerships have further enriched his research and contributions to the field.
Conclusion
Frank Buchholz is a leading figure in genetic engineering, with a focus on innovative methods for genome editing and retrovirus treatment. His patents reflect a commitment to advancing medical science and improving therapeutic options for genetic disorders.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile