The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Jan. 03, 2008
Joachim Hauber, Hamburg, DE;
Frank Buchholz, Dresden, DE;
Ilona Hauber, Hamburg, DE;
Francis a Stewart, Dresden, DE;
Indrani Sarkar, Kolkata, IN;
Joachim Hauber, Hamburg, DE;
Frank Buchholz, Dresden, DE;
Ilona Hauber, Hamburg, DE;
Francis A Stewart, Dresden, DE;
Indrani Sarkar, Kolkata, IN;
Abstract
The present invention is directed to a method for preparing an expression vector encoding a tailored recombinase, wherein said tailored recombinase recombines asymmetric target sites within the LTR of proviral DNA of a retrovirus inserted into the genome of a host cell and is useful as means for excising the provirus from the genome of the host cell. The present invention further relates to an in vitro-method of optimising the treatment of a retroviral infection of a subject and to the use of tailored recombinases for the preparation of pharmaceutical compositions for reducing the viral load in a subjected infected by a retrovirus.